The utility model relates to an air pressure hose with flange connectors and belongs to the field of air pressure tubes. The air pressure hose comprises a hose body and the quick connectors respectively connected to two ends of the hose body. The hose body comprises a plastic hose and protection tube sleeved outside the plastic hose. The quick connectors are provided with connecting flanges and connecting skirts, each connecting flange is fixedly connected with the corresponding connecting skirt, the connecting skirts are sleeved outside the ends of the hose body, and the connecting skirts are fixedly connected with the hose body through fastening rings. The air pressure hose with the flange connectors is applicable to connection of the air pressure tubes in industrial production, and the quick connectors arranged at two ends of the hose facilitate quick connecting and mounting; the hose body is provided with the protection tube which has the effect of protecting the inner tube (the plastic hose) and preventing the hose from being damaged in the industrial production.